The first
church, located on Shawmut Avenue, Boston, was consecrated on November 11, 1923. The edifice was named the Holy Trinity Church. Due largely to the exodus of parishioners to the Greater Boston suburbs, the church was relocated to Cambridge, MA. The new
magnificent edifice in Armenian architectural style stands at the corner of Brattle and Sparks Street near Harvard Square, and was
consecrated on September 17, 1961. The present pastor of the Holy Trinity Church is the Reverend Father Vasken A. Kouzouian.
Former Pastors:
| Rev. Fr. Mampre Kouzouian | 1977-2002 |
| Very Rev. Fr. Yeghishe Gizirian | 1975-1977 |
| Rev. Fr. Papken Maksoudian | 1952-1974 |
| Rev. Fr. Haroutune Toumayan | 1931-1951 |
| Fr. Shahe Altoonian | 1948-1951 |
| Very Rev. Fr. Hagop Mekhitarian | 1930-1931 |
| Rev. Fr. Yeghiazar Ashjian | 1930-1931 |
| Rev. Fr. Khoren Lazarian | 1930-1931 |
| Very Rev. Fr. Shahe Kasparian | 1920-1930 |
| Most Rev. Abp. Papken Guleserian | 1919 |
| Very Rev. Fr. Shahe Kasparian | 1913-1918 |
| Most Rev. Abp. Moushegh Seopian | 1911-1913 |
| Rev. Fr. Sarkis Tashjian | 1909-1911 |
| Rev. Fr. Hagop Paretchanian | 1908 |
| Rev. Fr. Theodoros Isahagian(Choughayetsi) | 1901-1907 |
| Very Rev. Fr. Khat Markarian | 1897-1898 |
| James M. Kalustian | 1999-2005 |
| George W. Haroutunian | 1993-1998 |
| Albert Zouranjian | 1989-1992 |
| Nancy D. Kasarjian | 1986-1988 |
| Stephen Panosian | 1982-1985 |
| Donald J. Tellalian | 1981 |
| Helene Dorian | 1978-1980 |
| Dr. Michael Kolligian, Jr. | 1976-1977 |
| Gregory Tashjian | 1975 |
| Richard Zeytoonjian | 1974 |
| Arthur Apkarian | 1971-1973 |
| Gregory Archie Kolligian | 1969-1970 |
| John Soursourian | 1967-1968 |
| Michael Gazarian | 1966 |
| John Davagian | 1965 |
| Gen. Sarkis Zartarian | 1961-1964 |